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A total of 96 outpatients were enrolled in the trial and randomized to receive 60 days of PT and ALA (600 mg/day) plus SOD (140 IU/day) (Group 1

Oxidative stress, free radicals, kidney disease and plant antioxidants

Apart from the genetic mutations, other experiments have proven that it is the lack of taurine conjugation to the tRNALeu(UUR) that leads to MELAS syndrome

For instance, inhibitors of ferroptosis, such as Ferrostatin-1, can reduce inflammatory responses in keratinocytes, which may be related to the modulation of Th17 cell functions (152)